Radiodensity Study of Hydroxyapatite Coated Porous Tantalum Implant Material of Rat Animal Model

摘要

The aim of this study was to find out the in-vivo radiography density changes of hydroxyapatite coated porous tantalum biomaterial implant after surgical implantation in rats. Ten adult male Sprague Dawley rats were divided into two groups: hydroxyapatite-coated porous tantalum (pTa-HAp) and uncoated porous tantalum (pTa). The implants with dimension of 5 x 2 x 0.5 mm~3 was inserted into flatten bone defects drilled at the femur bone on latero-medial region. The implant density from right lateral view radiogram was analyzed at day 0, 7, 14 and 30 post-implantation. The results showed that the radiodensity of both pTa and pTa-HAp groups decreased in time of implantation. The radiodensity changes of pTa-HAp showed higher decrease compared to pTa.