The AKT-mTOR Signalling Pathway in Kidney Cancer Tissues

机译：肾癌组织中的AKT-MTOR信号通路

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An increased expression of phospho-AKT, m-TOR, glycogen regulator GSK-3-beta and transcription inhibitor 4E-BP1 was observed in kidney cancer tissues. Tumor size growth was associated with a high level of c-Raf and low content of phospho-m-TOR. Cancer metastasis development led to a decreased PTEN and phospho-AKT expression.

机译：在肾癌组织中观察到磷酸-AKT，M-TOR，糖原调节剂GSK-3-Bβ和转录抑制剂4e-BP1的增加。肿瘤大小的生长与高水平的C-RAF和磷酸-M-TOR的低含量有关。癌症转移发育导致PTEN和磷酸磷酸盐的表达减少。

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《International Scientific Conference "New Operational Technologies"》|2015年|1 v. (various pagings) :|共5页
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L. V. Spirina; Y. A. Usynin; I. V. Kondakova; Z. A. Yurmazov; E. M. Slonimskaya; E. S. Kolegova;
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中图分类 R319-532;
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phospho-AKT; decreased PTEN; kidney cancer tissues;

机译：磷酸盐;降低PTEN;肾癌组织;

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1. MiR-21 modulates radiosensitivity of cervical cancer through inhibiting autophagy via the PTEN/Akt/HIF-1 alpha feedback loop and the Akt-mTOR signaling pathway [J] . Song Lili, Liu Shikai, Zhang Liang, Tumour biology : . 2016,第9期

机译：MiR-21通过抑制自噬通过PTEN / Akt / HIF-1 alpha反馈回路和Akt-mTOR信号通路来调节宫颈癌的放射敏感性
2. Oxamate-mediated inhibition of lactate dehydrogenase induces protective autophagy in gastric cancer cells: Involvement of the Akt-mTOR signaling pathway [J] . Zhao Zhi, Han Fanghai, Yang Shibin, Cancer letters . 2015,第1期

机译：草酸盐介导的乳酸脱氢酶抑制作用在胃癌细胞中诱导保护性自噬：涉及Akt-mTOR信号通路
3. The tumor-suppressor gene LZTS1 suppresses colorectal cancer proliferation through inhibition of the AKT-mTOR signaling pathway [J] . Wei Zhou, Mei-Rong He, Hong-Li Jiao, Cancer letters . 2015,第1期

机译：肿瘤抑制基因LZTS1通过抑制AKT-MTOR信号通路抑制结肠直肠癌增殖
4. The AKT-mTOR Signalling Pathway in Kidney Cancer Tissues [C] . L. V. Spirina, Y. A. Usynin, I. V. Kondakova, International Scientific Conference "New Operational Technologies" . 2015

机译：肾癌组织中的AKT-MTOR信号通路
5. Creating an embryonic kidney: The role of bone morphogenetic protein signaling during patterning and differentiation of pronephric tissue in Xenopus laevis. [D] . Bracken, Christina M. E. 2007

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7. SEXUAL DIFFERENCES IN THE CONTENT OF INSULIN-LIKE SIGNALING PATHWAY COMPONENTS IN KIDNEY TISSUES IN LOCAL AND GENERALIZED CLEAR CELL KIDNEY CANCER [O] . A.A. Breus, E.M. Frantsiyants, O.I. Kit, 2019

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8. Targeting Tissue Factor-Factor VIIa Signaling Pathway to Enhance Activity of mTOR Inhibitors in the Treatment of Breast Cancer [R] . Bromberg, M. 2010

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The AKT-mTOR Signalling Pathway in Kidney Cancer Tissues

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