Quenching and Suppression of Riboflavin-Photosensitized SingletOxygen Generation by Salicylic Acid Derivatives

摘要

Since the discovery the antipyretic and analgesic effects of willow leaves and barkcontaining salicylate,salicylic acid derivatives that are less irritating the digestive organs arenow widely used prescription drugs.Riboflavin,a vitamin B2,is an effective photosensitizerwidely found in human tissues and foods causing oxidative damage to proteins,other vitamins,sterols,and lipids upon absorption of UV-A and visible light.When oxidative damage occursin light-permeable organs and tissues,such as the human eye and skin,it can accelerateinflammation and aging.