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Analytical approaches for analysis of intracardiac bipolar electrograms during atrial fibrillation

机译:心房颤动期间肠腔双极电子图谱分析的分析方法

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Atrial fibrillation is the most common type of cardiac arrhythmias encountered in clinical practice, in which heart muscles shows chaotic atrial depolarization and uncoordinated contraction. Underlying mechanisms of atrial fibrillation are incompletely understood and widely discussed in the scientific community. The abnormal electrical discharges in atrial repolarization is associated with localized drivers and multiple wavefronts that support the asynchronous heart rhythm. In this paper, a briefly overview of conventional techniques focus on mapping drivers of myocardial fibrillation and their application are discussed. We also introduce a novel mapping algorithm which is aimed to identity features of wavefront propogation and analyze the relative changes of generalized instantaneous dominant frequency calculated from intracardiac recordings. Our clinical trials showed that proposed algorithm provides insightful and useful information about triggered abnormal activity during atrial fibrillation, that potentially can be used for catheter ablation therapy.
机译:心房颤动是在临床实践中遇到的最常见的心律失常类型,其中心肌显示混沌心房去极化和不协调的收缩。在科学界不完全理解和广泛讨论心房颤动的基础机制。心房复极性的异常电放电与局部驱动器和支持异步心律的多个波前相关联。本文简要概述了常规技术,重点关注映射心肌颤动的驱动器及其应用。我们还介绍了一种新颖的映射算法,该算法旨在具有波前漂移的特征,并分析从心内记录计算的广义瞬时显性频率的相对变化。我们的临床试验表明,所提出的算法在心房颤动期间提供了有关触发的触发异常活动的洞察力和有用的信息,这可能可用于导管消融治疗。

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