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Epidemiological survey of Streptococcus suis in the US swine population based on whole genome sequencing

机译:基于全基因组测序的美国猪群中猪群流行病学调查

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Streptococcus suis is a gram positive bacterium that causes septicemia, bronchopneumonia, arthritis, and fatal meningitis in young piglets. Piglets are usually infected through exposure to asymptomatic sows. Ihirty-five different serotypes of S. suishave been identified,1 however, recent work has suggested that only 29 unique serotypes exist.2'3 In addition, many isolates remain non-typeable using traditional methods. Of the 35 serotypes described, serotype 2 is most commonly associated with disease, but serotypes 1, 1/2, 3, 4, 5, 7, 8, 9 and 16 are also commonly isolated from diseased swine.' Newport Laboratories has developed a comprehensive, unambiguous method of capsular typing based on whole genome sequencing and bioinformatics. This method of typing is useful to type field and there arc no non-typeable serotypes.
机译:Screptococcus suis是革氏菌阳性细菌,导致败血症,支气管内血症,关节炎和幼小仔猪中的致命脑膜炎。仔猪通常感染到无症状母猪。鉴定了S. Suishave的iHirty-Five不同的血清型,1然而,最近的工作表明,只有29个独特的血清型,只有29个独特的血清型。另外,许多分离株使用传统方法保持不可键入。在所述35所描述的血清型中,血清型2是最常见的与疾病相关,但血清型1,11 / 2,3,4,5,7,8,9和16也通常从患病的猪中分离出来。基于全基因组测序和生物信息学,纽波特实验室开发了一种综合,明确的胶囊打字方法。这种键入方法对于键入字段非常有用,并且没有非键型的血清型。

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