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Comparison between 3D-CRT and Modulated Techniques for Head-and-Neck and Breast

机译:3D-CRT与头部颈部和乳房调制技术的比较

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Objective: Knowing that the most important steps related to planning systems and the success of IMRT is the optimization process, the objective of this work was to reach an optimal intensity pattern through cost functions by comparing the 3D-CRT technique and the IMRT technique for carcinomas of the head and neck and breast. The results obtained in the passage between these two techniques have shown good results for the treatment of these tumors and a great advantage in the optimization to avoid OAR. Materials and methods: To fulfill the objective proposed in this work for the head and neck plan, a SIB with a prescribed dose of 70 Gy for PTV1 and 56 Gy for PTV2 given in 35 fractions was used. In the breast plan with a prescribed dose of 50.4 Gy for PTV and 58.8 Gy for PTV boost delivered in 28 fractions. 6 MV and 10 MV photons were used for an Elekta Synergy linear accelerator, equipped with an MLC. Monaco was used as a TPS system. The Elekta iViewGT panel was used as the matrix for 2D quality control. The analysis of the data was done using the conformality index (CI) and the heterogeneity index (HI). A tolerance limit was proposed for quality control over 85% according to the hospital protocol. Results: Head and neck: The 3D technique and the 3 modulated techniques were able to meet the dose limit for PTV1 of D95%≥66.5 Gy and the dose for PTV2 of D95%≥ 53.2 Gy. The CI values for Step and Shoot and dMLC were the best for the PTV, as well as for the OARs such as the medulla and parotid. The PTV2d95 (Gy) of all techniques successfully exceeds the limit value of 53.2 Gy greatly satisfying the optimal intensity pattern using IMRT showing that the modulated techniques have better performance in these types of carcinomas. Breast: An acceptable plan with double-arch VMAT was achieved for the increase in dose coverage for 95% PTV (55.9 Gy) with 57.2 Gy. A difference of the four techniques was not significant in the spinal cord. The objective of this work is established w
机译:目的:知道与规划系统相关的最重要步骤以及IMRT的成功是优化过程,通过比较3D-CRT技术和癌的IMRT技术,通过成本函数来达到最佳强度模式。头部和颈部和乳房。在这两种技术之间的通过中获得的结果表明了治疗这些肿瘤的良好结果以及优化避免OAR的巨大优势。材料和方法:为了满足在这项工作中提出的目的,用于头部和颈部平面,使用具有规定剂量为70gy的PTV1和56GY的PTV2中的SIB,以35分级分。在乳房计划中,PTV的50.4Gy的规定剂量为58.8Gy,PTV提升以28分数递送。 6 MV和10 MV光子用于Elekta Synergy线性加速器,配备MLC。摩纳哥被用作TPS系统。 ELEKTA IVIEWGT面板用作2D质量控制的矩阵。使用相互性指数(CI)和异质性指数(HI)进行数据分析。根据医院协议,提出了耐受性限制以超过85%的质量控制。结果:头部和颈部:3D技术和3种调制技术能够满足D95%≥66.5GY的PTV1剂量限制,PTV2的剂量为D95%≥53.2GY。步骤和拍摄和DMLC的CI值是PTV的最佳,以及诸如髓质和腮腺等桨。所有技术的PTV2D95(GY)成功超过了使用IMRT的最佳强度模式的限制值53.2 GY,表明调节技术在这些类型的癌中具有更好的性能。乳房:使用57.2GY的95%PTV(55.9GY)的剂量覆盖增加,实现了具有双拱VMAT的可接受的计划。脊髓中四种技术的差异在脊髓中不显着。这项工作的目标是建立

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