A multi-well structure of light-addressable potentiometric sensor for measurement of a plurality of liquid samples

摘要

Simultaneous measurement of a plurality of analytical samples in a single step is advantageous for reduction of time and cost of laboratory assays. The light-addressable potentiometric sensor (LAPS) [1] offers a platform to integrate a large number of measurement spots on a single sensor plate, which can be accessed by addressing light beams. In this study, we developed a partially-etched structure [2] of LAPS, in which each of the etched region serves as a defined well to accommodate a liquid sample and produces larger photocurrent signals in a wider frequency bandwidth.