Monoclonal Antibodies as a Designed Protein Scaffold for Chiral Separation and Asymmetric Catalysis

摘要

Chirality is crucial in various field of science such as pharmaceuticals, organic synthesis and materials science. Therefore synthesis, separation and detection of chiral molecules have attracted great deal of attention. We have focused on chemically homogeneous antibodies, monoclonal antibodies (mAbs), as a chiral recognition element .