Surface Plasmon Resonance Imaging and Particle Size Analysis Solutions to Explore Biomolecular Interactions

摘要

Surface Plasmon Resonance imaging (SPRi) and Particle Size Analysis (PSA) are two complementary technologies to explore biomolecular interactions. Indeed, they can characterize biomolecular interactions by giving complementary information such as: Kinetics constants, affinity and concentration; Size, temperature of denaturation, aggregation. Surface Plasmon Resonance imaging (SPRi) is an optical technique which monitors label-free molecular interactions in a real-time and multiplex format. The multiplex format of SPRi allows ligands to be immobilized under different conditions for fast and easy comparison on a single sensor chip.