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Optimized formulation of APN toothpaste with biochemical materials using response surface methodology

机译:使用响应面方法优化具有生物化学材料的APN牙膏的制剂

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Response surface methodology(RSM) was used to optimize the formulation of one toothpaste with aglycone extracted from Panax notoginseng (APN). Biochemical materials are important components in toothpastes. The addition amount of APN, thickener, different ratios of humectant and friction agent were selected as three factors for the design. Our results showed that the experimental data could be adequately fitted into a second-order polynomial model. Addition amount of thickener and humectant: friction agent had a significant effect on the composite score. The optimum formulation for preparing APN toothpaste was predicted to be: APN, 0.12%; thickener, 1.58%; humectant: friction agent, 1.01.
机译:响应表面方法(RSM)用于优化从Panax Notoginseng(APN)中提取的糖苷剂的一种牙膏的制剂。生物化学材料是牙膏中的重要组成部分。选择APN,增稠剂,摩擦剂的不同比例的添加量为设计的三个因素。我们的研究结果表明,实验数据可以充分装配到二阶多项式模型中。增稠剂和保湿剂的添加量:摩擦剂对复合成绩具有显着影响。预计制备APN牙膏的最佳制剂是:APN,0.12%;增稠剂,1.58%;保湿剂:摩擦剂,1.01。

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