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TANK SIZE IN EXPERIMENTAL DESIGN MATTERS

机译:实验设计中的坦克大小

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During planning of experiments scientists frequently face the choice of experimental unit size. On the one hand, the experiments should be designed to mimic realistic large-scale farming situations as far as possible. On the other hand, smaller unitsare often preferred because running costs are lower, the conditions are easier to standardise, and it is more feasible to run many replicates. Furthermore, with reference to the three R's in animal research, small units enable reduction in number of animals. Despite advantages with small experimental units, professional staff at many research facilities have observed that unit size matters regarding fish performance in experiments, and that transfer of fish, especially from larger to smaller units, mayresult in weeks without normal feed intake. However, there are a few studies showing effects of scale on growth (Boeuf and Gaignon, 1989). In addition, the study by Boeuf and Gaignon (1989) had too few replicates (N=2) to enable statistical analyses andhence conclusions. The aim of this experiment was to investigate the effects of rearing tank scale, and different scaling histories on Atlantic salmon performance during five months.
机译:在规划实验期间,科学家经常面临实验单位尺寸的选择。一方面,实验应该设计为尽可能地模仿现实的大规模农业情况。另一方面,较小的单位通常优选,因为运行成本较低,条件更容易标准化,并且运行许多重复更加可行。此外,参考动物研究中的三个R,小单位能够降低动物数量。尽管具有小实验单位的优势,但许多研究设施的专业工作人员已经观察到在实验中的鱼类性能以及鱼类的转移,尤其是较小的单位,在没有正常的进料入口的情况下的较大单位的单位规模对鱼类的尺寸。然而,有一些研究表明规模对增长的影响(Boeuf和Gaignon,1989)。此外,Boeuf和Gaignon(1989)的研究太少了(n = 2),以实现统计分析的结论。该实验的目的是调查饲养罐规模的影响,以及在五个月内对大西洋三文鱼性能的不同缩放历史。

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