Detoxification of Cadmium on The Levels of Urea and Creatinine on Rattus Norvegicus with Tea Mistletoe (Scurrula Atropurpurea)

摘要

The present of cadmium in the body is nephrotoxic due to it's effect in increasing urea and creatinine. Tea mistletoe (Scurrula atropurpurea) has quercetin compound that able to become cadmium chelator. This study aims to know the effect and effective dose tea mistletoe as natural chelator in detoxifying cadmium towards urea and creatinine levels of male white rats (Rattus norvegicus). The study result obtained that all doses of tea mistletoe extract decreased urea and creatinine levels of rat that induced by cadmium. Effective dose of tea mistletoe extract that decreased urea and creatinine levels was 400 mg.kg~(-1) WB.