Recovery Does Not Prevent Myocardial Damage Due to Overtraining (Biomolecular and Pathobiology Studies)

摘要

Overtraining the body with exercises and without adequate recovery time would lead to various health conditions. The overtraining conditions, usually leads to oxidative stress which damages the body tissue. This study aims to analyze the effect associated with a recovery duration of three and seven days in order to prevent myocardial damage due to overtraining. The research made use of a post experimental test of 32 rats which were divided into 4 groups namely 1) proportional sport, 2) overtraining, 3) overtraining with recovery of 3 days and 4) overtraining with recovery of 7 days. Histopathology examination was performed at the end of the experiment period on the rats. The results obtained has it that there were myocardial damage in the left ventricular hypertrophy, necrosis and chromatin condensation of these rats. Posttest comparative analysis was done to analyze and obtain a posttest mean for each group. For MDA myocardium concentration, Analysis Of Variance (ANOVA) results showed F to be equal to 6,248 with p = 0,002; SOD myocardium concentration was F = 19.519 with p = 0.0001; Left Ventricular Hypertrophy Index was F = 140,732 with p = .0,0001; Index of myocardium necrosis between groups, was F = 201,911 with p = 0.0001; Chromatin condensation index on the cardiomyocyte between the study groups was F = 524,466 with p = 0.0001. Post hoc tests showed different significant concentration at MDA and SOD without any different in the left ventricular hypertrophy, necrosis and chromatin condensation. The results of this study proves that there is no effect inmyocardial damage as a result of overtraining from three and seven days, notwithstanding the fact that recovery decreases MDA myocardium concentrations, increases SOD myocardium concentrations, but does not prevent left ventricular hypertrophy, necrosis and chromatin condensation.