The Effects of Oral Glutathione Supplementation on Human Volunteers: An Observation on Metabolic Syndrome Status

摘要

Oral glutathione supplementation helps in improving metabolic syndrome status of human volunteers. Glutathione is a cluster of amino acid containing one molecule of L-glutamic acid, L-cysteine, and glycine each. It act as a master antioxidant that combat free radicals in cells and help in detoxification of chemical from our body. This study aim to observe the effects of glutathione on metabolic syndrome symptoms after 12 weeks of supplementation. Reflection of the effects were carried on fasting glucose, blood pressure, cholesterols, waist to hip ratio, body fat percentage and basic measurement such as body mass index and blood pressure. Volunteers were divided into two groups; Group 1: One dosage of 5 g supplement, Group 2: Two dosage of 5 g supplement. A total of 23 volunteers' have been recruited for the study. Based on the metabolic syndrome diagnosis we studied, out of 23, six subjects were found to have metabolic syndrome. After 12 week of supplementation, based on the parameter studied, there seems to be an improvement in the level of HDL cholesterol, body mass index (BMI), and waist to hip ratio for both group volunteers.