Preparation and application of dialdehyde pullulan for the construction of gelatin hydrogels

摘要

In this work,dialdehyde pullulans with different aldehyde contents were successfully prepared with periodate oxidization method and used as cross-linking agent for the construction of gelatin hydrogeis.It was found that aldehyde contents can be varied by changing pH of the aqueous phase.The highest oxidation degree as well as the content of dialdehyde groups was found at pH 4.0.The mechanical properties of the gelatin hydrogeis were significantly improved with the addition of dialdehyde puliulan.The fascinating reinforcing performance of the dialdehyde puliulan extends the potential application of hydrogeis in thebiomedical area.