Influence of Artificial Microgravity on Human Arterial Vessels

摘要

The aim of this work is to study the alterations occurred in human cardiovascular system under artificially simulated microgravity. Artificial gravity produced by short-arm centrifuge along the head-to-feet axis induces gravity gradients and causes hemodynamic alterations. We have used differential arterial blood pressure measurements, pulse wave contour analysis, and accelerated photo-plethysmography (APPG) to determine the impact of artificially simulated microgravity on human vascular system. The group of 50 healthy male volunteers was studied in a short-arm human centrifuge at normal gravity gradient of 1 Gz during 10 min at supine position lying at the nacelle. Blood pressure and APPG parameters registered before, during and after exposure of artificial gravity.