Aerobic exercise combined with Cervus and Cucumis Polypeptide Injection study on glucocorticoid induced osteoporosis treatment effect

摘要

Objective: Observe the deer melon polypeptide injection combined with aerobic exercise to glucocorticoids effect for the treatment of osteoporosis. Methods: selection of wenshan city, the first affiliated hospital of bone surgery in March 2013-November 2014 to receive glucocorticoids sex of osteoporosis patients in hospital, 220 cases were randomly divided into treatment group (110 cases) with deer melon polypeptide injection with aerobic exercise therapy, the control group (110 cases) taking calcium he D treatment, a course of 30 days, continuous treatment 3 period of treatment. Were observed before and after treatment of the femoral neck, lumbar (L1～L4) bone mineral density changes and blood serum calcium, phosphorus, alkaline phosphatase level changes; Results: treatment group and control group (L1～L4) of the lumbar spine, femoral neck BMD comparison (P<0.05), significantly increased, with statistical significance. Treatment group total effective rate was 94.5%, the control group was 86.3%, comparing the two groups (P<0.05) was statistically significant. Conclusion: deer melon polypeptide injection combined with aerobic exercise in treatment of glucocorticoid osteoporosis curative effect significantly, can significantly improve patients with bone loss rate, slow down the bone absorption, reduce the loss of bone mass, has the high feasibility and safety, no serious adverse reactions, worthy of clinical widely. Osteoporosis is a unit of volume reduction the amount of bone tissue, bone micro-structural damage, bone fragility chronic progressive disease, multiple fractures are the main clinical symptoms of the disease. According to the etiology of the osteoporosis divided into primary osteoporosis and secondary osteoporosis are two types of glucocorticoid-induced osteoporosis belong to drug-induced secondary osteoporosis. In Wenshan City First Affiliated Hospital of Orthopaedic Surgery in March 2013-2014 in November accommodated 220 cases of glucocorticoid osteoporosis patients for the study of hormones, deer melon polypeptide injection and aerobics glucocorticoid therapy osteoporosis efficacy discussed below.