AngiotensinI-converting enzyme (ACE) inhibitory activities from goat milk yoghurt supplemented with probiotic and roselle extract

摘要

Goat milk has several advantages such as milk whiter color, the size of the fat globules are smaller so it is more easily absorbed by the body and can be consumed by people with lactose intolerance, but the drawbackis the goaty odor. Processing technology can decrease the goaty odor such as fermentation. Probiotic bacteria also can improve the functional properties of fermented goat milk because of proteolytic activities, such as antyhipertensive function. Roselle flower has antioxidant capacity that can improve quality of yoghurt. The aim of the research was to evaluate angiotensinI-converting enzyme (ACE) inhibitory activities from goat milk yoghurt supplemented with probiotic and roselle extract. Treatments were (1) goat milk yoghurt, (2) goat milk yoghurt + probiotic L. acidophillus IIA-2B4, (3) goat milk yoghurt + Roselle extract, and (4) goat milk yoghurt + probiotic L. acidophillus IIA-2B4 + extract of Roselle. The result showed that probiotic L. acidophilus IIA-2B4 contributed in peptide fragments separation of yoghurt. Antihypertensive activities demonstrated that goat milk yoghurt was able to inhibit the angiotensin converting enzyme (ACE) activity an enzyme that plays a role in the renin angiotensin aldosterone system as a function of blood pressure regulation in human body.The ACE inhibitor activity of yoghurt probiotic roselle was higher than the yoghurt probiotic. The goat milk yoghurt supplemented by probiotic and roselle extract was met the Indonesian national standard of yoghurt and safe to be consumed.