TREATING SEPSIS IN DOGS AND CATS: WHAT ARE THE GOALS?

摘要

The severity of bacterial sepsis varies from patient to patient. Some patients will require advanced life support measures to survive while others will require only basic supportive care. The key aspects of sepsis treatment include 1.) initial resuscitation, 2.) alleviating the inciting cause and 3.) aggressive supportive care. The treatment of sepsis can be roughly organized into initial resuscitation (i.e., first 1-6 hours) and long-term management (i.e., > 6 hours to discharge from hospital). Initial resuscitation includes not only restoration of hemodynamic homeostasis, but also alleviating the inciting cause through administration of antimicrobial drugs and/or debridement. Recently, the concept of early goal directed therapy has become more prevalent in human medicine. Goal directed therapy is based on the idea of tailoring treatment to specific physiologic parameters thought to be associated with restoration of homeostasis and improved outcome.