Mixed beta-glucanase and xylanase from Disporotrichum dimorphosporum

摘要

At the request of the Codex Committee on Food Additives at its Forty-sixth Session (FAO/WHO, 2014), the Committee evaluated the safety of mixed (3-glucanase (3-(l,3;l,4)-(3-D-glucan 3(4) glucanohydrolase; Enzyme Commission No. 3.2.1.6) and xylanase (l,4-beta-D-xylan xylanohydrolase; Enzyme Commission No. 3.2.1.8)from Disporotrichum dimorphosporum. This enzyme preparation has not been evaluated previously by the Committee. The Committee evaluated several other enzyme preparations of f3-glucanase or xylanase at its thirty-first, thirty-fifth, thirty-ninth, sixty-first and sixty-third meetings and established an acceptable daily intake (ADI) "not specified" for their use in several applications, such as the preparation of beer and baking products (Annex 1, references 78, 88, 101, 167 and 174). In this report, theexpression "mixed f3-glucanase and xylanase liquid enzyme concentrate" is used when referring to the material tested in the toxicological studies evaluated; the expressions "(3-glucanase" and "xylanase" are used when referring to the enzymes and their amino acid sequences; and the expression "mixed beta-glucanase and xylanase enzyme preparation" is used when referring to the commercial enzvme preparation.