Co_(0.5)Fe_(2.5)O_4 Nanoparticle Biological Impact - Comparative Study on Environmental Cellulolytic Fungi

摘要

Cobalt ferrite nanoparticles (NPs) with potential medical utilization were prepared by co-precipitation being further electrostatically stabilized with perchloric acid in aqueous solution. XRD analysis revealed typical spinel lattice crystallites with less than 10 nm size, SEM evidenced rather uniform quasi-spherical shape of 45 nm average NP size, dynamical analysis of particle movement in diluted solution indicated average hydrodynamical diameter of 65 nm; magnetometric investigation revealed dominant superparamagnetic features. We studied some biochemical aspects of NPs impact following their release in the environment with focus on the oxidative stress induced in cellulolytic fungi (able of degrading cellulose waste). The increase in malondialdehyde content of fungi mycelium indicated lipid peroxidation which could be correlated with the changes observed in catalase and superoxide dismutase activity. Different sensitivity to iron and cobalt ions was noticed in the studied fungi strains.