Single-Photon Emission Computed Tomography with ~(199)Tl in Diagnostics of Malignant Tumors of the Larynx and Laryngopharynx

摘要

The purpose of research was to investigate the diagnostic capabilities of single-photon emission computed tomography (SPECT) with ~(199)Tl in the diagnostics of malignant tumors of the larynx and laryngopharynx. The study included patients with primary and recurrent malignant tumors of the larynx or laryngopharynx, and patients with benign diseases of the larynx. All patients underwent SPECT of the larynx after intravenous administration of ~(199)Tl. It turned out that SPECT with ~(199)Tl is an effective method for diagnosing laryngeal and laryngopharyngeal cancer, having indices of sensitivity, specificity, and accuracy of 95%, 100% and 96.7% respectively. According to our data, in the visualization of regional metastases the sensitivity of SPECT with ~(199)Tl has amounted to 75%.