The development of fusion energy is one of the important International energy strategies with the important milestone is ITER (International Thermonuclear Experimental Reactor) project, initiated by many countries, such as: America, Europe, and Japan who agreed to set up TOKAMAK type fusion reactor in France. In ideal fusion reactor the fuel is purely deuterium, but it need higher temperature of reactor. In ITER project the fuels are deuterium and tritium which need lower temperature of the reactor. In this study tritium for fusion reactor can be produced by using reaction of lithium with neutron in the blanket region. With the tritium breeding blanket which react between Li-6 in the blanket with neutron resulted from the plasma region. In this research the material used in each layer surrounding the plasma in the reactor is optimized. Moreover, achieving self-sufficiency condition in the reactor in order tritium has enough availability to be consumed for a long time. In order to optimize Tritium Breeding Ratio (TBR) value in the fusion reactor, there are several strategies considered here. The first requirement is making variation in Li-6 enrichment to be 60%, 70%, and 90%. But, the result of that condition can not reach TBR value better than with no enrichment. Because there is reduction of Li-7 percent when increasing Li-6 percent. The other way is converting neutron multiplier material with Pb. From this, we get TBR value better with the Be as neutron multiplier. Beside of TBR value, fusion reactor can analyze the distribution of neutron flux and dose rate of neutron to know the change of neutron concentration for each layer in reactor. From the simulation in this study, 97% neutron concentration can be absorbed by material in reactor, so it is good enough. In addition, it is required to analyze spectrum neutron energy in many layers in the fusion reactor such as in blanket, coolant, and divertor. Actually material in that layer can resist in high temperature and high pressure condition for more than ten years.
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