Solid-state grafting of poly(ethylene glycol) onto alginic acid

摘要

Melt reaction of poly(ethylene glycol) and alginic acid (guluronate-rich and mannuronate-rich) was studied. The poly(ethylene glycol) was end-capped with reactive amino group while the sodium alginate was converted to alginic acid before melt reaction. The melt reaction kinetics of poly(ethylene glycol) and alginic acid were monitored by differential scanning calorimetry. The reaction temperatures were ranged between 75 and 96 °C, below the degradation temperature of both parent polymers. The reactive amino group of poly(ethylene glycol) reacted with carboxyl group of alginic acid. The rate of reaction increased with reaction temperature.