EVALUATION ON THE POTENTIAL WITH CHANNEL-TYPE AND CAGE-TYPE METAL-ORGANIC FRAMEWORKS AS ABSORBENTS IN SOLID-PHASE MICROEXTRACTION

摘要

In 1990, Arthur and Pawliszyn proposed for the first time the concept of solid-phase microextraction (SPME) that is nowadays has widely been used in the analysis for pharmaceutical, food, forensic, biological, environmental samples and so on. Metal-organic frameworks (MOF) have been the focus of much attention very recently because of the uniqueness of their properties that brought unprecedented potentials for diverse applications. Several studies have also been developed in the fabrication of SPME using MOF, but most cases using physical coating mode to fix MOF particles on fiber (i.e. fiber SPME). As a result, the preparation of MOF on fiber and conditioning of SPME fiber is time consuming (>1 day) and with limited stability and reproducibility. To overcome the above drawbacks, in this study, several MOF materials are embedded in organic polymer monoliths via microwave-assisted copolymerization of methacrylate ester based monomers, in which the preparation of SPME extraction column could be completed within 10 min. The prepared MOF-polymers are utilized successfully as adsorbents in SPME for extracting antibiotics from water or dairy samples.