Enzymatic Degradation of Chitosan blend for Tissue Engineering Application

摘要

Chitosan has adaptable applications in skin, cartilage and bone tissue engineering. This study was concentrated on the enzymatic degradation of chitosan. The degradation was carried out during four weeks of incubation at (37 °C) temperature in media phosphate buffer saline solution containing lysozyme. The samples were characterized using Fourier transformations infrared spectroscopy (FTIR), degree of swelling, antimicrobial activity. Through the degradation interval, higher and slower weight loss of chitosan films was remarkable in medium degradation. The degradation behavior of chitosan was important parameters that utilized for bone tissue engineering.