Synthesis of Guanosine-contalning Dinucleoside Triphosphates

摘要

Dinucleoside polyphosphates have potential medicinal value and are of substantial interest to both synthetic and medicinal chemists. A practical method for the synthesis of guanosine-containing asymmetrical dinucleoside triphosphates (Gp3C and Gp3U) with 4,5-dicyanoimidazole as activator has been developed.