Analytical strategies for a systematic characterization of nanoparticle release from commercial spray products for exposure quantification and risk assessment

摘要

Nanoparticle containing sprays are categorized as critical consumer products due to their direct exposure path via lungs. Recent studies proposed first analytical concepts for simulated exposure experiments and proper risk assessment. Nevertheless these studies lack from systematic evaluation. This work aims on providing necessary knowledge for identification of the most critical nanoparticle types and consumer spray application. The goal is to provide optimization and validation of analytical concepts for proper quantification and a proportion of guidelines for appropriate analytical simulation experiments.