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Standardization of the Cryopreservation Process for Parathyroid Glands

机译:甲状旁腺冷冻保存方法的标准化

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The treatment of secondary Hyperparathyroidism may require cryopreservation of parathyroid glands to allow autotransplant. So far, cryopreservation and cryostorage has been done by the clinicians themselves. In some cases, investment in necessary equipment was not effective due to the small number of cases. In this paper, we evaluate a new combination of cryopreservation and transportation processes. The intention was to facilitate cryopreservation in the hospital and to store the tissue in a facility conforming to GMP. The tissue is stored in the gas phase of liquid nitrogen (LIN) in a cryostorage vessel. Tissue viability and function can be kept high to optimise the overall results. The high cryopreservation standards and the necessary equipment allows hospitals to use Good Storing Practice (GSP) and to reduce process costs. At the central facility, a new standard of storing tissue has been introduced, which enables a closed cooling chain and automated data collection as well as the storage of the tissue.
机译:继发性甲状旁腺功能亢进的治疗可能需要冷冻保存甲状旁腺,以允许自同胶。到目前为止,临床医生本身已经完成了冷冻保存和冷冻蒸气机。在某些情况下,由于较少的案例,对必要设备的投资无效。在本文中,我们评估了冷冻保存和运输过程的新组合。目的是促进医院的冷冻保存,并将组织存放在符合GMP的设施中。将组织储存在低温蒸发容器中的液氮(LIN)的气相中。组织活力和功能可以保持高度以优化整体结果。高冷冻保存标准和必要的设备允许医院使用良好的储存实践(GSP)并降低流程成本。在中央设施,已经引入了新的存储组织标准,这使得封闭的冷却链和自动数据收集以及组织的储存。

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