Diagnostic Accuracy of Magnetic Resonance Myocardial Perfusion Imaging for diagnosis of functionally significant obstructive coronary artery disease. A systematic review

摘要

Introduction: Ischaemic heart disease (IHD) as a consequence of untreated Coronary arterial disease (CAD) is one of the top three causes of mortality[1] and the most common cause of morbidity in developed countries[1 2], therefore early diagnosis is important. Cardiac magnetic resonance perfusion imaging(CMR) is one of the non-invasive techniques that had shown to be safe in diagnosis of haemodynamically obstructive intraluminal coronary lesion. Several small studies have evaluated diagnostic performance of CMR and some have been included in previous meta-analysis( Hamon M,2010[3] and Nandalur KR,2007[4]) which compared it to Quantitative Coronary angiogram(QCA). Due to the fact that QCA often provides insufficient information regarding physiological significant of the coronary lesions we performed a contemporary meta-analysis of CMR diagnostic accuracy compared with an invasive pressure-wire guided fractional flow