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Experimental analysis of potential micrornas encoded during and after Blood brain barrier disruption

机译:血脑屏障破坏期间和血型脑屏障中断后潜在的microRNA的实验分析

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MicroRNAs (miRNAs) regulate gene expression and have a critical role in many biological processes in health and disease conditions. Recent studies showed that Blood-brain barrier (BBB) break down is directly leading to brain dysfunction and damage. We thus hypothesized that miRNA expression profiles in brain subjected to different insults to the BBB would show common as well as unique miRNA expression profiles.
机译:microRNAs(miRNA)调节基因表达,在许多生物过程中具有关键作用,健康和疾病病症。 最近的研究表明,血脑屏障(BBB)分解直接导致脑功能障碍和损伤。 因此,假设大脑中脑中的miRNA表达谱对BBB不同的侮辱将显示出常见的和独特的miRNA表达谱。

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