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A novel optical calorimetry dosimetry approach applied to an HDR Brachytherapy source

机译:一种新型光学量热法,适用于HDR近距离放射治疗源

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The technique of Digital Holographic Interferometry (DHI) is applied to the measurement of radiation absorbed dose distribution in water. An optical interferometer has been developed that captures the small variations in the refractive index of water due to the radiation induced temperature increase ΔT. The absorbed dose D is then determined with high temporal and spatial resolution using the calorimetric relation D=cΔT (where c is the specific heat capacity of water). The method is capable of time resolving 3D spatial calorimetry. As a proof-of-principle of the approach, a prototype DHI dosimeter was applied to the measurement of absorbed dose from a High Dose Rate (HDR) Brachytherapy source. Initial results are in agreement with modelled doses from the Brachyvision treatment planning system, demonstrating the viability of the system for high dose rate applications. Future work will focus on applying corrections for heat diffusion and geometric effects. The method has potential to contribute to the dosimetry of diverse high dose rate applications which require high spatial resolution such as microbeam radiotherapy (MRT) or small field proton beam dosimetry but may potentially also be useful for interface dosimetry.
机译:数字全息干涉测量法(DHI)的技术应用于水中辐射吸收剂量分布的测量。已经开发了一种光学干涉仪,其捕获由于辐射诱导温度升高ΔT而捕获水折射率的小变化。然后使用量热关系D =CΔT(其中C是水的比热容量,用高时和空间分辨率测定吸收的剂量D.该方法能够时间分辨3D空间量热法。作为该方法的原理证据,将原型DHI剂量表从高剂量率(HDR)近距离放射治疗源的测量应用于吸收剂量。初始结果与来自BrachyVision治疗计划系统的建模剂量一致,证明了系统的高剂量率应用的可行性。未来的工作将专注于应用热扩散和几何效果的校正。该方法具有促进不同于需要高空间分辨率的多种高剂量率应用的剂量率,例如Microbeam放射疗法(MRT)或小型现场质子束剂量测定法,但可能对界面剂量测定法也可用。

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