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Cascaded microring resonators for biomedical applications: improved sensitivity at large tuning range

机译:用于生物医学应用的级联微管谐振器:在大调谐范围内提高了灵敏度

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The progress in bioanalytics caused a growing demand of innovation in reliable, miniaturized and low cost optical sensor systems based on integrated optical devices. We present a detailed analysis of sensor elements for applications in aqueous solution based on two cascaded microring resonators (MRRs) by using the Vernier effect (VE). This approach is beneficial for ultra-high sensitivity at large fabrication tolerances, aspects of crucial importance for the practical detection of biomolecules such as peptides. The architecture consists of two silicon nitride microrings connected via a bus waveguide. The free spectral range (FSR) of individual rings is slightly different in order to achieve VE. Thereby the external refractive index of the reference ring is fixed; the second one varies due to the presence of the analyte. The precise operation is controlled by using spectral tuning via integrated micro-heaters. Theoretical analysis has been performed for different structural parameters. A sensitivity several orders of magnitude higher than in the case of a single ring can be predicted for TE and TM polarization, respectively. The first design of Vernier devices and its experimental characterization will be presented. The devices include tapered grating couplers in order to couple light between fibers and chip at moderate alignment tolerances in a reliable manner. Therefore, by combining the VE and the spectral tuning, cascaded MRRs are an optical configuration very promising for sensing applications.
机译:生物分析性的进展在基于集成光学器件的可靠,小型化和低成本光学传感器系统中的创新需求不断增长。我们通过使用vernier效应(VE)对基于两个级联的微管谐振器(MRRS)的水溶液中的传感器元件进行了详细的分析。这种方法对大型制造公差的超高敏感性有益,对于实际检测生物分子如肽的实际检测至关重要的方面。该结构由通过总线波导连接的两种氮化硅微孔组成。为了实现VE,单个环的自由谱​​范围(FSR)略有不同。从而固定了参考环的外部折射率;第二个由于分析物的存在而变化。通过使用集成的微加热器使用光谱调谐来控制精确的操作。已经针对不同的结构参数进行了理论分析。可以预测TE和TM偏振的敏感性高于单环的情况的数量级高。将提出第一个Vernier设备设计及其实验表征。该装置包括锥形光栅耦合器,以便以可靠的方式在适度的对准公差之间耦合纤维和芯片之间的光。因此,通过组合VE和光谱调谐,级联的MRR是光学配置非常有前途的感测应用。

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