This study aimed at investigating the perception of toothpaste flavors during tooth brushing. The 3D geometrical model of human oral cavity and nasal cavity was built. The dynamic concentration of investigated flavor limonene under certain tidal volume was obtained with computational fluid dynamics (CFD) technology. It was found that the designed taste could be reached within half minutes for limonene. According to the data within 180 s, the taste did not changed significantly during the whole brushing time. Tidal volume was crucial for the perception for the toothpaste.
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