ADVANCED COMPUTER MODELING FOR INTERSTITIAL MICROWAVE HYPERTHERMIA THERAPY: Comparison of Two Numerical Methods in Computational Electromagnetics

摘要

Microwave hyperthermia therapy is a recent development in the field of tumor ablation. Eelectromagnetic microwave irradiation applied to the tumor tissue causes water molecules to vibrate and rotate, resulting in tissue heating and subsequently cell death via thermal-induced protein denaturation. To effectively treat deep-stead tumors, the interstitial antennas should produce a highly localized specific absorption rate pattern and be efficient radiators at different generator frequencies. Numerical electromagnetic and thermal simulations are used to optimize the antenna design and predict heating patterns. An advanced computer modeling of a double slot antenna for interstitial hyperthermia was designed using two different numerical methods, the Finite Element Method and a Finite-difference time-domain. The aim of this work is to compare and analyze both numerical methods.