Optimized Formula with Linear Programming Model for Anticancer Production of Marine Fungus

摘要

In order to promote the yield of anticancer chemical compound PJ157 of marine YUP08 strain, the Linear Programming model (LP model) was used to optimize four components of medium for the strain. The primary culture medium consists of glucose, peptone, yeast and NaCl, which were possessory worked on growing and metabolism of the fungus. Contribution rate from data was built to manage complex effects for produce PJ157. It is forecast that the yield of PJ157 could be increased to 0.21735 mg/L which was great more than 0.04 mg/L in the before. Therefore the LP model could be used for fermentation optimization of microorganism.