Toxicology and Medical (PPT)

摘要

The weisht-of-evidence suggests that exposures below 5 ppb TWA in the absence of peak exposures above 20 ppb are unlikely to produce chronic lung effects in non-sensitized individuals. Diisocyanates appear to be capable of causing respiratory injury at concentrations below irritation and odor thresholds. The potential occurrence of occupational asthma warrants attention particularly with spraying and other operations that may generate diisocyanate particles or vapors.