The Isolation of Endogenous Mesenchymal Stem Cells Residing in Intestinal Submucosa Using a Niche-Preserving Organ Culture System

摘要

Here, we established a fibrin-supported 3D organ culture system that was able to verify the presence of MSCs in IS. We also successfully recapitulated the MSC niche residing in IS in vitro and defined their in situ pericyte-like nature.