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Mining Adverse Drug Side-Effects from Online Medical Forums

机译:来自在线医学论坛的采矿不良药物副作用

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Pharmaceutical drugs prescribed for the prevention, treatment or cure of diseases can have adverse reactions or side-effects that lead to further health complications or sometimes even death. Most of the common side-effects of drugs, reported by their manufacturer, are based on clinical trials. However, not all possible side-effects are identified, as their detection is limited by the extent of the number and diversity of the participants in the trials. Online medical help forums where patients voluntarily provide feedback on the drugs they take, provide an excellent source for identifying the unreported side-effects of drugs. Mining for these side-effects would help patients make informed decisions about the suitability of a drug for their treatment and also for health authorities to take appropriate action against drug manufacturers. In this paper we present a Hidden Markov Model based text mining system that can be used to extract adverse side-effects of drugs from online medical forums.
机译:用于预防,治疗或治愈疾病的药物可能具有不良反应或副作用,导致进一步的健康并发症或有时甚至死亡。其制造商报告的药物的大多数常见副作用是基于临床试验。然而,并非所有可能的副作用都被识别,因为它们的检测受到试验中参与者的数量和多样性的限制。在线医疗帮助论坛,患者自愿提供对他们所采取的药物的反馈,提供了一种识别药物未报告的副作用的优秀来源。对这些副作用的采矿将有助于患者对药物适合其治疗的适用性做出明智的决定,并为卫生当局对药品制造商采取适当行动。在本文中,我们介绍了一个基于隐马尔可夫模型的文本挖掘系统,可用于从在线医学论坛中提取药物的不良副作用。

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