Preparation and Chiral Resolution Properties of L-Phenylalanine Modified Poly(NIPAAm-co-AAc) Hydrogels

摘要

Poly(NIPAAm-co-AAc) hydrogels of different ratios were prepared by copolymerization and then modified with L-phenylalanine by amidation of carboxyl groups of acrylic acid. The structures of the hydrogels were identified by IR and the chiral separation experiments of hydrogels on D/L-phenylalanine were investigated. The results showed that the chiral hydrogels exhibited enantioselectivity for L-phenylalanine and the resolution capability increased with the rising of temperature and contents of L-phenylalanine groups.