Synthesis and glucose-sensitivity of composite hydrogels containing immobilized phenylboronic acid

摘要

The PBA-containing hydrogels were produced by copolymerizing 3-acrylaminophenylboronic acid with acrylamide. Hydrogels swelling increases steadily with pH and glucose concentration. The boronate specific dye, Alizarin Red S(ARS) was incorporated into hydrogels film. Alizarin Red S displays a dramatic change in fluorescence intensity and color in response to binding to boronic acid. The sensitivity of hydrogels is improved significantly.