Synthesis, Characterization and Properties of Poly(L-lactic acid-co-á- phenylalanine) Obtained by Direct Melting Copolymerization

摘要

A new poly(ester amide)s (PEA) derived from L-lactic acid and L- phenylalanine have been synthesized by melting copolymerization with p-toluenesulfonic acid (TSA), stannous chloride (SnCl_2) as catalyst. The products were analyzed by NMR, FT IR. The effects of the content of L-phenylalanine on the copolymers structure were studied. Being the phosphate buffered saline (pH=7.2) as the degradation solution, it had been found that the degradation rate speed up with the increasing the content of the L- phenylalanine.