TRANSSPHENOIDAL SURGERY FOR PITUITARY ADENOMAS IN DOGS WITH PITUITARY DEPENDENT HYPERADRENOCORTISOLISM USING A HIGH DEFINITION VIDEO TELESCOPE: METHODS AND RESULTS

摘要

Pituitary dependent hyperadrenocorticism (PDH) has a reported incidence of 0.2% of all dogs, or ~ 100,000 dogs yearly in the United States.1' 2 Most dogs diagnosed with PDH have truncal weight gain, a pendulous or sagging abdomen, ravenous appetite, hair loss, skin changes, and polyuria/polydipsia. If untreated or non-responsive to therapy, pituitary tumors may enlarge causing compression of the hypothalamus and surrounding brain structures resulting in anorexia, cachexia, diabetes insipidus, somnolence, seizures, and eventually death.