Wound dehiscence of an intestinal anastomosis often leads to generalized bacterial peritonitis and subsequent death. Therefore, factors which negatively affect visceral healing are potentially of great clinical significance to the surgeon. Factors that cause intestinal anastomoses to leak include etiology of obstruction, failure to adequately identify ischemic tissue, improper suturing or stapling technique and factors that negatively effect wound healing such as sepsis, malnutrition and anti-neoplastic therapy.
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