ANESTHESIA CONCERNS FOR PATIENTS WITH ADRENAL DYSFUNCTION

摘要

Why should be we be aware of adrenal status? The adrenal cortex produces two major types of steroid hormones. These are the mineralocorticoids and the glucocorticoids. The mineralocorticoids are important in the maintenance of electrolyte balance which in turn also works to control blood pressure. The glucocorticoids work in the regulation of metabolism whether indirectly or directly through interactions with other hormones. Glucocorticoids regulate protein, fat, carbohydrate and nucleic acid metabolism. Blood glucose is raised by antagonizing the secretion and action of insulin. Glucocorticoids cause protein catabolism and fat mobilization. Anti-inflammatory action is due to effects on microvasculature and suppression of inflammatory cytokines.