Study of circulating slox-1 (soluble lectin-like oxidized ldl receptor -1) and oxidative stress in acute stroke

摘要

Neurovascular oxidative stress in acute stroke may be a potential marker of advancing ischemic brain injury. We investigate neurovascular oxidative stress during the first 24 hours onset of acute stroke patients in order to determine changes of sLOX-1 and circulating NO levels. Changes of decreased NO and elevated sLOX-1 levels in significant stenosis flow (SSF) group are greater than non-significant stenosis flow (NSSF) group. We conclude that neurovascular oxidative stress was advanced during 24 hours and was subsequent effect from vascular oxidative stress of carotid stenosis.