TYPE IV PILI OF NEISSERIA MENINGITIDIS FIVE PTM'S ONE EXPERIMENT A COMPARISION OF ECD AND ETD FOR COMPREHENSIVE FRAGMENTATION

摘要

For the gram negative bacterium Neisseria meningitidis, host cell adhesion, bacterial aggregation and colony dissemination are key pathogenic stages all moderated by type IV pili. These filamentous bacterial organelles are principally composed of the 17.5kDa protein pilE, which is arranged in a helical fashion to create the strong and flexible polymer aggregate observed as the pilus.