Food additives or Cosmetic ingredients in Plygonum cuspidatum

摘要

Seven compounds were isolated from the leaves of polygonum cuspidatum, and their structures were established on basis of MS and NMR spectroscopy. They were 3-O-caffeoyl quinic acid (1), quercetin 5-O-Fucosyl(1-2)-rhamnoside (2), (-)-epica-techin (3), procyanidin B-2 (4), procyanidin C (5), procyanidin E (6), 3'-trimethoxy procyanidin E (7). As a result, remarkable hyaluronidase inhibitory activity was indicated to proanthocyanidin compounds. Subsequently we evaluated isolated compounds for a collagenase inhibitory activity examination and the histamine liberation inhibition test by using human juvenile basophil cell line KU812. In conclusion, it might be used in general as food additives or cosmetics because remarkable antiallergic activity which had moisturizing action was found from the leaves of Polygonum cuspidatuma.