Research Progress on Tissue Engineering of Neural Stem Cells

摘要

Neural stem cells (NSCs), as therapeutic agents, play the key role in the treatment of central nervous system (CNS) disorders. It is a researching tendency for promote proliferation and differentiation of neural stem cells by using tissue engineering. It is discovered that joint use neural stem cells and NSCs-seeded scaffold may increase the cell survival state and better control cellular microenvironment. We find suitable material include natural biological materials, synthetic materials, compound materials, bio-derived materials and 3D-materials of neural stem cells tissue engineering by analyzing and summing up of the research which combine tissue engineering with NSCs transplant in past several years. It hold out a hope of the possibility of utilizing the treatment of neural stem cells transplantation with tissue engineering, and there has been a great quantity of achievements on the research of it to treat CNS disorders by promote proliferation and differentiate.