Ultra-sensitive label-free biosensing by using single-mode coupledmicrocavity laser

摘要

We report that by using a single mode coupled microcavity laser, we successfully realized a sensitivity of 80 pg/ml for detecting BSA. The detecting scheme also works for other bio samples. The result proves that active sensing with microcavity laser can achieve ultrahigh sensitivity. Further analysis shows that the ultra-sensitivity comes from the slight change of coupling coefficient between the two coupled microcavities.